Epidemiological analysis of nifedipine and phenytoin-induced gingival overgrowth in users of the Primary Health Care System
نویسندگان
چکیده
Methods: Demographic, pharmacological, and periodontal data were obtained from 100 users of the Brazilian Primary Health Care System in Diamantina, Jequitinhonha Valley, Minas Gerais state, Brazil, who were taking nifedipine and/or phenytoin. Clinical evaluations including gingival overgrowth analysis were carried out by a single calibrated examiner. Bivariate analysis (Chi-square test or Student’s t-test) were used to identify demographic, periodontal and drugrelated significant factors associated with gingival overgrowth severity. Multivariate analysis (Poisson regression) was used to assess confounding factors.
منابع مشابه
Drug-Induced Gingival Hyperplasia
This article has summarized observations and results of controlled laboratory and clinical studies of drug-induced gingival hyperplasia associated with phenytoin, cyclosporine, and nifedipine use. Furthermore, information regarding the pharmacologic aspects of these medications is presented. More information is needed for a greater understanding of drug-induced gingival hyperplasia. It appears ...
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